Signaling peptide receptor

Template:Short description Signaling peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins.

An example is the tropomyosin receptor kinase B (TrkB), which is bound and activated by the neurotrophic protein brain-derived neurotrophic factor (BDNF). Another example is the μ-opioid receptor (MOR), which is bound and activated by the opioid peptide hormone β-endorphin.

Adiponectin receptor

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AdipoR₁

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Agonists
- Peptide
- Non-peptide
Antagonists
- Peptide
  - ADP-400

AdipoR₂

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Agonists
- Peptide
- Non-peptide
Antagonists
- Peptide
  - ADP-400

Angiotensin receptor

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Bradykinin receptor

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Agonists
- Bradykinin
- Kallidin
Antagonists

Calcitonin gene-related peptide receptor

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Agonists
- Amylin
- CGRP
- Pramlintide
Antagonists
- Atogepant
- BI 44370 TA
- CGRP (8-37)
- MK-3207
- Olcegepant
- Rimegepant
- SB-268262
- Telcagepant
- Ubrogepant
Antibodies

Cholecystokinin receptor

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CCK_A

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Agonists
- Cholecystokinin
Antagonists

CCK_B

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Agonists
Antagonists

Unsorted

Antagonists
- Nastorazepide

Corticotropin-releasing hormone receptor

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CRF₁

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Agonists
Antagonists
- Antalarmin
- Astressin-B
- CP-154,526
- Emicerfont
- Hypericin
- LWH-234
- NBI-27914
- NBI-74788
- Pexacerfont
- R-121919
- TS-041
- Verucerfont

CRF₂

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Agonists
Antagonists
- Astressin-B

Cytokine receptor

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Endothelin receptor

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Agonists
Antagonists
- A-192621
- Ambrisentan
- Aprocitentan
- Atrasentan
- Avosentan
- Bosentan
- BQ-123
- BQ-788
- Clazosentan
- Darusentan
- Edonentan
- Enrasentan
- Fandosentan
- Feloprentan
- Macitentan
- Nebentan
- Sitaxentan
- Sparsentan
- Tezosentan
- Zibotentan

Galanin receptor

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GAL₁

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Agonists
Antagonists
- C7
- Dithiepine-1,1,4,4-tetroxide
- Galantide (M15)
- M32
- M35
- M40
- SCH-202596

GAL₂

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Agonists
- Galanin
- Galanin (1-15)
- Galanin (2-11)
- Galanin-like peptide
- Galmic
- Galnon
- J18
- NAX 810-2
Antagonists
- C7
- Galantide (M15)
- M32
- M35
- M40
- M871

GAL₃

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Agonists
- Galanin
- Galanin (1-15)
- Galmic
- Galnon
Antagonists
- C7
- Galantide (M15)
- GalR3ant
- HT-2157
- M32
- M35
- M40
- SNAP-37889
- SNAP-398299

Growth hormone secretagogue receptor

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Growth hormone receptor

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Growth-hormone-releasing hormone receptor

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Glucagon-like peptide receptor

GLP-1

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Agonists

GLP-2

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Agonists

Others

Propeptides
- Preproglucagon
- Proglucagon

Glucagon receptor

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Agonists
Antagonists
Propeptides
- Preproglucagon
- Proglucagon

Gonadotropin-releasing hormone receptor

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Gonadotropin receptor

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Growth factor receptor

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Insulin receptor

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Agonists
Antagonists
- BMS-754807
- S661
- S961
Kinase inhibitors
- Linsitinib
Antibodies
- Xentuzumab (against IGF-1 and IGF-2)

KiSS1-derived peptide receptor

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Agonists
Antagonists
- Kisspeptin-234

Leptin receptor

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Agonists
- Leptin
- Metreleptin

Melanin-concentrating hormone receptor

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MCH₁

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Agonists
- Melanin-concentrating hormone
Antagonists
- ATC-0065
- ATC-0175
- GW-803430
- NGD-4715
- SNAP-7941
- SNAP-94847

MCH₂

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Agonists
- Melanin-concentrating hormone

Melanocortin receptor

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Neuropeptide FF receptor

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Agonists
Antagonists
- BIBP-3226
- RF9

Neuropeptide S receptor

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Agonists
- Neuropeptide S
Antagonists
- ML-154
- SHA-68

Neuropeptide Y receptor

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Y₁

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Agonists
- Neuropeptide Y
- Peptide YY
Antagonists
- BIBO-3304
- BIBP-3226
- BVD-10
- GR-231118
- PD-160170

Y₂

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Agonists
Antagonists

Y₄

Agonists
Antagonists
- UR-AK49

Y₅

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Agonists
Antagonists
- CGP-71683
- FMS-586
- L-152,804
- Lu AA-33810
- MK-0557
- NTNCB
- Velneperit (S-2367)

Neurotensin receptor

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NTS₁

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Agonists
- Neurotensin
- Neuromedin N
Antagonists
- Meclinertant
- SR-142948

NTS₂

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Agonists
- Neurotensin
Antagonists
- Levocabastine
  - SR-142948

Opioid receptor

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Orexin receptor

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Oxytocin receptor

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Prolactin receptor

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Parathyroid hormone receptor

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Agonists

Relaxin receptor

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Agonists
- Insulin-like factor 3
- Relaxin (1, 2, 3)
- Serelaxin

Somatostatin receptor

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Tachykinin receptor

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Thyrotropin-releasing hormone receptor

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Agonists

Thyrotropin receptor

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Agonists
- Thyrotropin alfa
- TSH (thyrotropin)

Vasopressin receptor

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Vasoactive intestinal peptide receptor and Pituitary adenylate cyclase-activating peptide

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VIPR₁

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Agonists
- Peptide
  - Bay 55-9837
  - LBT-3393
  - PACAP
  - VIP

VIPR₂

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Agonists
- Peptide
  - LBT-3627
  - PACAP
  - VIP

PAC₁

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Agonists
Antagonists
- PACAP (6-38)

Unsorted

Others

Endogenous
- Adrenomedullin
- Apelin
- Asprosin
- Bombesin
- Calcitonin
- Carnosine
- CART
- CLIP
- DSIP
- Enteroglucagon
- Formyl peptide
- GALP
- GIP
- GRP
- Integrin ligands
  - collagens
  - fibrinogen
  - fibronectin
  - laminins
  - ICAM-1
  - ICAM-2
  - osteopontin
  - VCAM-1
  - vitronectin
- Kininogens
- Motilin
- Natriuretic peptides
  - ANP
  - BNP
  - CNP
  - urodilatin
- Nesfatin-1
- Neuromedin B
- Neuromedin N
- Neuromedin S
- Neuromedin U
- Obestatin
- Osteocalcin
- Resistin
- Secretin
- Thymopoietin
- Thymosins
- Thymulin
- Urotensin-II
- VGF
Exogenous
- Lifitegrast (LFA-1 antagonist)

References

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External links

Template:MeshName

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Signaling peptide receptor

Adiponectin receptor

AdipoR1

AdipoR2

Angiotensin receptor

Bradykinin receptor

Calcitonin gene-related peptide receptor

Cholecystokinin receptor

CCKA

CCKB

Unsorted

Corticotropin-releasing hormone receptor

CRF1

CRF2

Cytokine receptor

Endothelin receptor

Galanin receptor

GAL1

GAL2

GAL3

Growth hormone secretagogue receptor

Growth hormone receptor

Growth-hormone-releasing hormone receptor

Glucagon-like peptide receptor

GLP-1

GLP-2

Others

Glucagon receptor

Gonadotropin-releasing hormone receptor

Gonadotropin receptor

Growth factor receptor

Insulin receptor

KiSS1-derived peptide receptor

Leptin receptor

Melanin-concentrating hormone receptor

MCH1

MCH2

Melanocortin receptor

Neuropeptide FF receptor

Neuropeptide S receptor

Neuropeptide Y receptor

Y1

Y2

Y4

Y5

Neurotensin receptor

NTS1

NTS2

Opioid receptor

Orexin receptor

Oxytocin receptor

Prolactin receptor

Parathyroid hormone receptor

Relaxin receptor

Somatostatin receptor

Tachykinin receptor

Thyrotropin-releasing hormone receptor

Thyrotropin receptor

Vasopressin receptor

Vasoactive intestinal peptide receptor and Pituitary adenylate cyclase-activating peptide

VIPR1

VIPR2

PAC1

Unsorted

Others

See also

References

External links

Navigation menu

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AdipoR₁

AdipoR₂

CCK_A

CCK_B

CRF₁

CRF₂

GAL₁

GAL₂

GAL₃

MCH₁

MCH₂

Y₁

Y₂

Y₄

Y₅

NTS₁

NTS₂

VIPR₁

VIPR₂

PAC₁