Devazepide
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Template:Short description Template:Drugbox
Devazepide[1] (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABAA receptors and instead acting as an CCKA receptor antagonist.[2] It increases appetite and accelerates gastric emptying,[3][4] and has been suggested as a potential treatment for a variety of gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux.[5] It is also widely used in scientific research into the CCKA receptor.[6][7]
Synthesis
Devazepide is synthesised in a similar manner to other benzodiazepines.[8][9]
See also
References
- ↑ <templatestyles src="Citation/styles.css"/>Template:Citation/make link, Evans, Ben E.; Freidinger, Roger M. & Bock, Mark G., "Benzodiazepine analogs", published Script error: No such module "auto date formatter"., assigned to Merck & Co. Inc.Script error: No such module "Check for unknown parameters".
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- ↑ <templatestyles src="Citation/styles.css"/>Template:Citation/make link, Jackson, Karen, "The use of devazepide as analgesic agent", published Script error: No such module "auto date formatter"., assigned to ML Laboratories plcScript error: No such module "Check for unknown parameters".
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