Rs6311
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In genetics, rs6311 is a gene variation—a single nucleotide polymorphism (SNP)—in the human HTR2A gene that codes for the 5-HT2A receptor. 5-HT2A is a neuroreceptor, and several scientific studies have investigated the effect of the genetic variation on personality, e.g., personality traits measured with the Temperament and Character Inventory[1][2][3][4] or with a psychological task measuring impulsive behavior.[5] The SNP has also been investigated in rheumatology studies.[6][7]
Some research studies may refer to this gene variation as a C/T SNP,[2] while others refer to it as a G/A polymorphism in the promoter region, thus writing it as, e.g., −1438 G/A or 1438G>A.[8][9][10]
since 2008[update]Template:Dated maintenance category (articles)Script error: No such module "Check for unknown parameters"., meta-analysis of research studies indicates that people with the A-allele may have slightly elevated risk of schizophrenia.[11]
rs6313, rs6314, and rs7997012 are other investigated SNPs in the HTR2A gene.
References
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