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...very high affinity to the [[Imidazoline receptor|I₂ imidazoline receptor]] (K_i = 40&nbsp;pM).<ref name="pmid8828003">{{cite journal | vau {{Imidazoline receptor modulators}} ...

...t]] and also has high [[affinity (pharmacology)|affinity]] for the [[sigma receptor]], possibly playing a role in its atypical neuroleptic action.<ref name="pm {{Dopamine receptor modulators}} ...

! Receptor !! K_i (nM) !! Notes | [[5-HT1A receptor|5-HT_1A]] || 17.3 || ...

{{Adrenergic receptor modulators}} {{Dopamine receptor modulators}} ...

...ethylation of [[dextromethorphan]] by [[CYP2D6]]. Dextrorphan is an [[NMDA receptor antagonist|NMDA antagonist]] and contributes to the psychoactive effects of ...url = https://pdsp.unc.edu/databases/pdsp.php?knowID=0&kiKey=&receptorDD=&receptor=&speciesDD=&species=&sourcesDD=&source=&hotLigandDD=&hotLigand=&testLigandD ...

{{Monoamine metabolism modulators}} {{Sigma receptor modulators}} ...

...}}</ref> (±)-18-MC competitively inhibits α9α10 [[nicotinic acetylcholine receptor|nAChRs]] with potencies higher than that at α3β4 and α4β2 nAChRs and direct ...se compounds were also found to act as selective [[ganglion type nicotinic receptor|α₃β₄ nicotinic acetylcholine antagonists]], with litt ...

...cts.<ref>{{Cite journal |last=Cott |first=J. M. |date=1997 |title=In vitro receptor binding and enzyme inhibition by Hypericum perforatum extract |url=https:// {{Glutamate receptor modulators}} ...

...ceptor|D₄ receptors]] and the [[5-HT7 receptor|5-HT₇ receptor]]. It is also a [[hERG]] [[channel blocker|blocker]]. ...has a high affinity for the [[Dopamine D2 receptor|dopamine D₂ receptor]] and this likely results in its sexual (due to [[Hyperprolactinaemia|prola ...

...lic]]; [[Hallucinogen]]; [[Serotonin]] [[5-HT2A receptor|5-HT_2A receptor]] [[agonist]] | [[5-HT1A receptor|5-HT_1A]] || 1,678–>5,600 ...

| [[5-HT1A receptor|5-HT_1A]] || 200–270 || Human | [[5-HT1B receptor|5-HT_1B]] || 1415 || Human ...

...tam]] and [[nebracetam]] show some affinity for [[muscarinic acetylcholine receptor]]s, only [[nefiracetam]] demonstrates nanomolar interactions with neurotran ...H, Oswald RE | title = Piracetam defines a new binding site for allosteric modulators of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) recepto ...

| [[5-HT1A receptor|5-HT_1A]] || >10,000 | [[5-HT1B receptor|5-HT_1B]] || >10,000 ...

| Name = ERG2/Sigma-1 receptor |Name=Sigma intracellular receptor 2 ...

| class = [[Serotonin]]; [[5-HT2 receptor|5-HT₂ receptor]] [[agonist]]; [[Serotonergic psychedelic]]; [[Hallucinogen]] ...rnal | vauthors = Luethi D, Liechti ME | title = Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoa ...

| class = [[Serotonin receptor agonist]]; [[Serotonergic psychedelic]]; [[Hallucinogen]] ...rnal | vauthors = Luethi D, Liechti ME | title = Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoa ...

| class = [[Serotonin]]; [[5-HT2 receptor|5-HT₂ receptor]] [[agonist]]; [[Serotonergic psychedelic]]; [[Hallucinogen]] | [[5-HT1A receptor|5-HT_1A]] || 470–916 ...

| class = [[Serotonin]] [[5-HT2 receptor|5-HT₂ receptor]] [[agonist]]; [[Serotonergic psychedelic]]; [[Hallucinogen]] | [[5-HT1A receptor|5-HT_1A]] || 190–740 (K_i)<br />>10,000 ({{Abbrlink|EC< ...

...in]]. Pergolide acts on many of the same receptors as dopamine to increase receptor activity. ...JM | title = Safety Pharmacology assessment of drugs with biased 5-HT(2B) receptor agonism mediating cardiac valvulopathy | journal = Journal of Pharmacologic ...

...url = https://pdsp.unc.edu/databases/pdsp.php?knowID=0&kiKey=&receptorDD=&receptor=&speciesDD=&species=&sourcesDD=&source=&hotLigandDD=&hotLigand=&testLigandD | [[5-HT1A receptor|5-HT_1A]] || 145–2829 || {{abbr|ND|No data}} || <ref name="PDSP" ...