Haloperidol decanoate
Template:Short description Template:Drugbox
Haloperidol decanoate, sold under the brand name Haldol Decanoate among others, is a typical antipsychotic which is used in the treatment of schizophrenia.[1][2][3][4] It is administered by injection into muscle at a dose of 100 to 200 mg once every 4 weeks or monthly.[5][6][7] The dorsogluteal site is recommended.[5] A 3.75-cm (1.5-inch), 21-gauge needle is generally used, but obese individuals may require a 6.5-cm (2.5-inch) needle to ensure that the drug is indeed injected intramuscularly and not subcutaneously.[5] Haloperidol decanoate is provided in the form of 50 or 100 mg/mL oil solution of sesame oil and benzyl alcohol in ampoules or pre-filled syringes.[5][6][8] Its elimination half-life after multiple doses is 21 days.[9][10] The medication is marketed in many countries throughout the world.[2][11]
Template:Pharmacokinetics of long-acting injectable antipsychotics
See also
References
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- 4-Phenylpiperidines
- Antipsychotic esters
- Butyrophenone antipsychotics
- 4-Chlorophenyl compounds
- Decanoate esters
- 4-Fluorophenyl compounds
- Drugs developed by Johnson & Johnson
- Janssen Pharmaceutica
- NMDA receptor antagonists
- Prodrugs
- Prolactin releasers
- Suspected embryotoxicants
- Suspected fetotoxicants
- Tertiary alcohols
- Typical antipsychotics