Rs7341475

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In genetics, rs7341475 is a single nucleotide polymorphism (SNP) in the RELN gene that codes the reelin protein. The gene RELN is mapped to human chromosome 7 (7q22.1). The SNP rs7341475 is located in the fourth intron of RELN. The gene RELN has many more SNPs among its 65 exons and 64 introns, — even in intron 4 there are tens of SNPs.[1]

The SNP has been investigated for a possible link to schizophrenia. A 2008 genome-wide association study pointed to that a variant of the SNP could elevate the risk for schizophrenia among women.[2] A 2015 publication reported a meta-analysis across five studies concluding a slight effect of the SNP.[3]

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