REPS2
Template:Short description Template:Cs1 config Script error: No such module "Unsubst". Template:Infobox gene RalBP1-associated Eps domain-containing protein 2 is a protein that in humans is encoded by the REPS2 gene.[1][2][3]
Function
The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.[3]
Interactions
REPS2 has been shown to interact with EPN1,[4] EPS15[5] and RALBP1.[1]
References
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Further reading
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