MCM5

Template:Short description Template:Cs1 config Template:Infobox gene DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene.

Function

The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

See also

• Mini Chromosome Maintenance

Interactions

MCM5 has been shown to interact with:

• Cell division cycle 7-related protein kinase,
• MCM2,
• MCM3,
• MCM7,
• ORC2L,
• ORC6L, and
• STAT1.

Further reading

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