MAP4K1
Jump to navigation
Jump to search
Template:Cs1 config Template:Short description Template:Infobox gene Mitogen-activated protein kinase kinase kinase kinase 1 is a protein kinase that in humans is encoded by the MAP4K1 gene.[1] It is also known as HPK1 (Hematopoietic Progenitor Kinase 1). The protein has been shown to play a role in JNK activation.[2]
Interactions
MAP4K1 has been shown to interact with:
<templatestyles src="Div col/styles.css"/>
Script error: No such module "Check for unknown parameters".
Optimization of inhibitors of MAP4K1 for upregulating the T cell receptor signaling pathway has produced at least one compound that exhibits antitumor activity in an EMT6 syngeneic mouse model, and is an area of ongoing research.[10]
References
<templatestyles src="Reflist/styles.css" />
- ↑ Script error: No such module "Citation/CS1".
- ↑ Script error: No such module "citation/CS1".
- ↑ Script error: No such module "Citation/CS1".
- ↑ a b c Script error: No such module "Citation/CS1".
- ↑ a b c d Script error: No such module "Citation/CS1".
- ↑ a b c d e Script error: No such module "Citation/CS1".
- ↑ Script error: No such module "Citation/CS1".
- ↑ Script error: No such module "Citation/CS1".
- ↑ a b Script error: No such module "Citation/CS1".
- ↑ Script error: No such module "Citation/CS1".
Script error: No such module "Check for unknown parameters".