HLA-B73

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Template:Short description

major histocompatibility complex (human), class I, B73
Alleles B*7301
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7301
Locus chr.6 6p21.31

HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product.[1] Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes.[2] B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

B*73:01 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*55:03.[3]

B73 serotype recognition of B*7301 allele-group gene products[4]
B*73 B73 Other Sample
allele % % size (N)
7301 22 69 106

B*7301 frequencies

HLA B*7301 frequencies
freq
ref. Population (%)
[5] Parsi (Karachi, Pakistan) 4.9
[5] United Arab Emirates 2.0
[5] Italy 2.0
[5] Seri (Sonora, Mexico) 1.5
[5] Purépecha (Michoacán, Mexico) 1.5
[5] Jews (Israel) (*2 studies) 1.2
[5] Beti (Cameroon) 1.1
[5] Casablanca (Morocco) 0.9
[5] Tbilisi (Georgia) 0.9
[5] Mossi (Burkina Faso) 0.9
[5] Bulgaria 0.9
[5] Sudanese 0.8
[5] Tuva (Russia) (2) 0.8
[5] Oman 0.8
[5] Bamileke (Cameroon) 0.6
[5] Pathan (Pakistan) 0.5
[5] Khalkha (Mongolia) 0.5
[5] Druse Arabs (Israel) 0.5
[5] Baloch (Iran) 0.5
[5] Manchester (England) 0.5
[5] Algeria (1) 0.5
[5] Turkey 0.4
[5] Amman (Jordan) 0.3
[5] Shona (Harare, Zimbabwe) 0.2
[5] Republic of Macedonia 0.2
[5] Nandi (Kenya) 0.2
[5] Luo (Kenya) 0.2
[5] Campania (Italy) 0.2
[5] Greece 0.2

References

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