HLA-B55

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Template:Short description

major histocompatibility complex (human), class I, B55
Alleles B*5501, B*5502
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5501
B*5502
Locus chr.6 6p21.31

HLA-B55 (B55) is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products.[1] (For terminology help see: HLA-serotype tutorial)

Serotype

B*55:03 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*73:01.[2]

B55 and B22 serotype recognition of some HLA B*55 allele-group gene products[3]
B*55 B55 B22 Sample
allele % % size (N)
5501 92 5 453
5502 84 2 309

Allele distribution

HLA B*5501 frequencies
freq
ref. Population (%)
[4] India New Delhi 3.8
[4] Singapore Chinese Han 3.5
[4] Spain Eastern Andalusia Gipsy 3.5
[4] Georgia Tbilisi Kurds 3.4
[4] India North Delhi 3.3
[4] France South East 3.1
[4] Israel Arab Druse 3.0
[4] India North Hindus 2.9
[4] Georgia Tbilisi Georgians 2.8
[4] Russia Tuva (2) 2.8
[4] Georgia Svaneti Svans 2.5
[4] Iran Baloch 2.5
[4] Singapore Thai 2.5
[4] Sudanese 2.5
[4] Mexico Mestizos 2.4
[4] Spain Eastern Andalusia 2.4
[4] Ireland South 2.0
[4] Azores Central Islands 1.8
[4] Bulgaria 1.8
[4] Israel Ashkenazi and Non Ashkenazi Jews 1.8
[4] Oman 1.7
[4] Tunisia Tunis 1.7
[4] India Andhra Pradesh Golla 1.4
[4] China Tibet 1.3
[4] Uganda Kampala 1.2
[4] Finland 1.1
[4] Portugal North 1.1
[4] Portugal Centre 1.0
[4] Singapore Riau Malay 1.0
[4] B*5502
[4] Taiwan Taroko 14.5
[4] American Samoa 12.0
[4] China Guangxi Maonan 6.0
[4] Japan Ainu Hokkaido 5.0
[4] China Tibet Autonomous Region Tibetans 4.7
[4] Singapore Chinese 3.0
[4] China Beijing Shijiazhuang Tianjian Han 2.9
[4] China North Han 2.9
[4] South Korea (3) 2.7
[4] Hong Kong Chinese 2.2
[4] Japan (5) 2.2
[4] Taiwan Ami 2.0
[4] Thailand (3) 2.0
[4] New Caledonia 1.0
[4] Philippines Ivatan 1.0

References

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