HLA-A43
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HLA-A43 (A43) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α43 subset of HLA-A α-chains. For A43, the alpha "A" chain are encoded by the HLA-A<templatestyles src="Template:Color/styles.css" />*43 allele group and the β-chain are encoded by B2M locus.[1] This group currently is dominated by A*4301. A43 and A<templatestyles src="Template:Color/styles.css" />*43 are almost synonymous in meaning. A43 is a split antigen of the broad antigen serotype A10. A43 is a sister serotype of A25, A26, A34, and A66. Script error: No such module "labelled list hatnote". A43 is more common in Africa and SouthWest Asia. A43 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.[2].
Serotype
| A*43 | A43 | A<templatestyles src="Template:Color/styles.css" />26 | Sample |
| allele | % | % | size (N) |
| *4301 | 0 | <templatestyles src="Template:Color/styles.css" />35 | 9 |
A43 serotyping is poor.
Distribution
| freq | ||
| ref. | Population | (%) |
| [4] | South Africa Tswana | 4.9 |
| [4] | South African Natal Zulu | 3.0 |
| [4] | China Yunnan Han | 1.2 |
| [4] | Zambia Lusaka | 1.2 |
| [4] | Pakistan Karachi Parsi | 0.6 |
| [4] | India North Delhi | 0.5 |
| [4] | Zimbabwe Harare Shona | 0.4 |
| [4] | Italy | 0.01 |
| [4] | China Shanghai | 0.002 |
References
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