Dienestrol

Template:Short description Template:Drugbox Dienestrol (INNTooltip International Nonproprietary Name, USANTooltip United States Adopted Name) (brand names Dienoestrol, Denestrolin, Dienol and many othersTemplate:Efn), also known as dienoestrol (BANTooltip British Approved Name), is a synthetic nonsteroidal estrogen medication of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe.^[1]^[2]^[3]^[4] It has been studied for use by rectal administration in the treatment of prostate cancer in men as well.^[5] The medication was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.^[4] Dienestrol is a close analogue of diethylstilbestrol.^[6] It has approximately 223% and 404% of the affinity of estradiol at the ERα and ERβ, respectively.^[7]

Dienestrol diacetate (brand names Faragynol, Gynocyrol, others) also exists and has been used medically.^[2]

Isomers

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