Cefonicid
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Cefonicide (or cefonicid) is a cephalosporin antibiotic.[1]
It has a density of 1.92g/cm3.
Synthesis
Injectable semi-synthetic cephalosporin antibiotic related to cefamandole, q.v.
Cefonicid is synthesized conveniently by nucleophilic displacement of the 3-acetoxy moiety of 1 with the appropriately substituted tetrazole thiole 2. The mandelic acid amide C-7 side chain is reminiscent of cefamandole.
See also
References
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- ↑ Script error: No such module "Citation/CS1".
- ↑ <templatestyles src="Citation/styles.css"/>Template:Citation/make link, Berges, David Alan, "Cephalosporin-Derivate [Cephalosporin derivatives]", published Script error: No such module "auto date formatter"., assigned to SmithKline Corp.Script error: No such module "Check for unknown parameters".
- ↑ D. A. Berges, U.S. patent 4048311 (1977 to Smith Kline).
- ↑ U.S. patent 4093723, U.S. patent 4159373 (1978, 1979 both to Smith Kline).
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