Cefazaflur
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Template:Short description Template:Drugbox
Cefazaflur (INN) is a first-generation cephalosporin antibiotic.
Synthesis
Cefazaflur stands out among this group of analogues because it lacks an arylamide C-7 side chain (see cephacetrile for another example).
Cefazaflur is synthesized by reaction of 3-(1-methyl-1H-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (1) with trifluoromethylthioacetyl chloride (2).
References
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