WDR26

Template:Short description Template:Cs1 config Template:Infobox gene WD repeat-containing protein 26 is a protein that in humans is encoded by the WDR26 gene.

Function

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Clinical significance

Pathogenic variants of the gene cause Skraban–Deardorff syndrome.