Varacin
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| Template:Longitem | C10H13NO2S5 |
| Molar mass | 339.540 g/mol |
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Varacin is a bicyclic organosulfur compound originally found in marine Ascidiacea from the Polycitor genus.[1] It contains an unusual pentathiepin ring which reacts with DNA, and varacin and synthetic analogues have been investigated for their antimicrobial and antitumour properties.[2][3] Because of its potent biological activity and unusual and challenging ring system, it has been a popular target of efforts toward its total synthesis.[4][5][6]
By virtue of the unsymmetrically substituted benzopentathiepin ring system, varacin and a few related polysulfane natural products exist as potentially isolable enantiomers as a result of planar chirality.[7]
References
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