U.S. Route 164
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Template:Use mdy dates U.S. Route 164 may refer to:
- U.S. Route 164 (Texas–Oklahoma) from Amarillo, Texas to Enid, Oklahoma; became part of US 60 in 1930
- U.S. Route 164 (Arizona–Colorado) from near Tuba City, Arizona to Cortez, Colorado; became part of US 160 in about 1970