Tropine
Tropine is a derivative of tropane containing a hydroxyl group at the third carbon. It is also called 3-tropanol.[1] It is a poisonous white hygroscopic crystalline powder.[2] It is a heterocyclic alcohol and an amine.[2]
Tropine is a central building block of many chemicals active in the nervous system, including tropane alkaloids. Some of these compounds, such as long-acting muscarinic antagonists are used as medicines because of these effects.[3]
Occurrence
Tropine is a natural product found in the plants of deadly nightshade (Atropa belladonna) and devil's trumpet (Datura stramonium).[4]
Chemistry
Synthesis
It can be prepared by hydrolysis of atropine[5] or other solanaceous alkaloids.[2]
See also
References
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