Trans-aconitate 2-methyltransferase

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Template:Infobox enzyme In enzymology, a trans-aconitate 2-methyltransferase (EC 2.1.1.144) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + trans-aconitate S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate

Thus, the two substrates of this enzyme are S-adenosyl methionine and trans-aconitate, whereas its two products are S-adenosylhomocysteine and (E)-3-(methoxycarbonyl)pent-2-enedioate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2P35.

References

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