Tiropramide
Jump to navigation
Jump to search
Template:Short description Template:Cs1 config Template:Drugbox
Tiropramide is the International nonproprietary name of an antispasmodic drug.[1]
Synthesis
The acylation of racemic tyrosine (1) with benzoyl chloride gives N,O-dibenzoyl-tyrosine (2). Amide formation with dipropylamine (3) using the mixed anhydride method gives the intermediate (4). Hydrolysis of the phenolic ester with sodium hydroxide forms (5), which is alkylated with Template:Chem2 to produce the ether tiropramide.[2][3]
References
<templatestyles src="Reflist/styles.css" />
- ↑ Script error: No such module "Citation/CS1".
- ↑ Francesco Makovec, Luigi Rovati, Paolo Senin, U.S. patent 4004008 (1977 to Rotta Research Laboratorium S.P.A.)
- ↑ Script error: No such module "citation/CS1".
Script error: No such module "Check for unknown parameters".
Script error: No such module "Navbox".