Tinidazole
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Tinidazole, sold under the brand name Tindamax among others, is a medication used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of anaerobic amoebic and bacterial infections. It was developed in 1972 and is a prominent member of the nitroimidazole antibiotic class.[1]
It is on the World Health Organization's List of Essential Medicines.[2]
Medical uses
Tinidazole may be a therapeutic alternative in the setting of metronidazole intolerance. Tinidazole is used to treat Helicobacter pylori, Amoebic dysentery, Giardia and Trichomonas vaginalis.[3]
Side effects
Drinking alcohol while taking tinidazole causes an unpleasant disulfiram-like reaction, which includes nausea, vomiting, headache, increased blood pressure, flushing, and shortness of breath.Template:Medcn
Pharmacology
Pharmacokinetics
Elimination half-life is 13.2 ± 1.4 hours. Plasma half-life is 12 to 14 hours.Template:Medcn
History
Tinidazole was approved for treatment of bacterial vaginosis in the United States in 2007.[4]
See also
References
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