Thiocyanate hydrolase

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Template:Infobox enzyme A thiocyanate hydrolase (EC 3.5.5.8) is an enzyme belonging to the family of hydrolases. The systematic name of this enzyme class is thiocyanate aminohydrolase. This enzyme catalyzes the chemical reaction:

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The mechanism is proposed to involve a metal thiocyanate complex.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 2DD4, 2DD5, 2DXB, and 2DXC.

A second thiocyanate hydrolase with copper at its active site catalyzes its conversion to cyanate:[1]

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References

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