TRISPHAT
Template:Chembox TRISPHAT (full name tris(tetrachlorocatecholato)phosphate(1−)) is an inorganic anion with the formula Template:Chem/link often prepared as the tributylammonium (Template:Chem/link) or tetrabutylammonium (Template:Chem/link salt. The anion features phosphorus(V) bonded to three tetrachlorocatecholate (Template:Chem/link) ligands. This anion can be resolved into the axially chiral enantiomers, which are optically stable (the picture shows the Δ enantiomer).
The TRISPHAT anion has been used as a chiral shift reagent for cations.[1] It improves the resolution of 1H NMR spectra by forming diastereomeric ion pairs.
Preparation
The anion is prepared by treatment of phosphorus pentachloride with tetrachlorocatechol followed by a tertiary amine gives the anion:
- PCl5 + 3 C6Cl4(OH)2 → H[P(O2C6Cl4)3] + 5 HCl
- H[P(O2C6Cl4)3] + Bu3N → Bu3NH+ [P(O2C6Cl4)3]−
Using a chiral amine, the anion can be readily resolved.[2]
References
<templatestyles src="Reflist/styles.css" />
Script error: No such module "Check for unknown parameters".