TNS1

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Template:Short description Template:Infobox gene Tensin-1 is a protein that in humans is encoded by the TNS1 gene.[1]

The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined.[1]

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Further reading

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