TLC

Arts and entertainment

TLC (TV series), a 2002 British situational comedy television series that aired on BBC2
TLC (TV network), formerly the Learning Channel, an American cable TV network
- TLC (Asia), an Asian television channel
- TLC (Australian TV channel), the Australian and New Zealand TV channel Travel and Living Channel
- TLC (French TV channel), a French television channel
- TLC (German TV channel), a German television channel
- TLC (India), an Indian television channel
- TLC (Latin America), a television channel broadcasting to several countries in Latin America
- TLC (Middle East and North Africa)
- TLC (Dutch TV channel), a Dutch television channel, which broadcasts lifestyle programs
- TLC (Poland), a Polish television channel
- TLC (Swedish TV channel), a Swedish television channel
- TLC (Turkish TV channel), a Turkish television channel
- TLC (UK and Irish TV channel), a UK and Ireland television channel
- Discovery Real Time, a former UK television channel originally known as The Learning Channel

TLC (group), an American R&B/pop group
- TLC (album), 2017 album by American R&B/pop group TLC
"T.L.C.", a song on the album Show Your Hand by the Scottish funk and R&B band Average White Band

Tables, ladders, and chairs match, a type of professional wrestling match
- WWE TLC: Tables, Ladders & Chairs, a professional wrestling event featuring the above type of match

New York City Taxi and Limousine Commission, a New York City government agency
Taiwan Lutheran Church, church in Taiwan
Tasmanian Land Conservancy, Australian non-profit organisation
The Land Conservancy, a not-for-profit, charitable land trust based in British Columbia, Canada
The Learning Company, an American educational software company
- SoftKey, a Canadian shovelware company which acquired The Learning Company and used its name from 1995 to 1999
TLC Camp, American nonprofit providing summer camp for children with cancer
Trades and Labor Congress of Canada, the primary labor federation in Canada (1883-1956)
Transitional Learning Center, a post-acute brain injury rehabilitation facility based in Galveston, Texas
Transgender Law Center, an American civil-rights organization connecting transgender people to legal services
True and Living Church of Jesus Christ of Saints of the Last Days, an offshoot of The Church of Jesus Christ of Latter-day Saints
The Literary Consultancy, a UK-based editorial consultancy service

Thayer Learning Center, a boot camp for teens in Missouri, US
The Learning Center for the Deaf, a school for the deaf and hard of hearing in Massachusetts, US
The Lakes College, a private school in Brisbane, Australia

Technology life cycle, describes the commercial gain of a product through the expense of research and development phase, and the financial return during its "vital life"
Therapeutic Lifestyle Change, a treatment for depression
Thin-layer chromatography, a chromatography technique used in chemistry to separate chemical compounds
Total lung capacity, refers to the volume of air associated with different phases of the respiratory cycle
Triple-level cell, a type of flash memory
Tank Landing Craft, a British WWII landing craft, US called Landing craft tank
Triple lumen catheter