TIMP4

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Template:Short description Template:Cs1 config Template:Infobox gene Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene.[1][2][3]

This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.[3]

Interactions

TIMP4 has been shown to interact with MMP2.[4][5]

See also

References

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Further reading

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External links

  • The MEROPS online database for peptidases and their inhibitors: I35.004