TESK1
Template:Short description Template:Cs1 config Template:Infobox gene Dual specificity testis-specific protein kinase 1 is an enzyme that in humans is encoded by the TESK1 gene.[1][2]
Function
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.[2]
Interactions
TESK1 has been shown to interact with YWHAB[3] and SPRY4.[4]
References
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Further reading
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