Stollé synthesis

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Template:Use dmy dates The Stollé synthesis is a series of chemical reactions that produce oxindoles from anilines and α-haloacid chlorides (or oxalyl chloride).[1][2][3][4]

The Stollé synthesis
The Stollé synthesis

The first step is an amide coupling, while the second step is a Friedel–Crafts reaction.[5][6] An improved procedure has been developed.[7][8]

See also

References

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