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...[[complement system]] of the [[innate immune system]]. C7 is part of the [[complement membrane attack complex|membrane attack complex (MAC)]] which creates a hol * [[Terminal complement pathway deficiency]] ...

'''Properdin''' is a [[protein]] that in humans is encoded by the CFP (complement factor properdin) [[gene]]. ...e [[C3-convertase|C3]] and [[C5-convertase]] enzyme complexes to form an [[Complement membrane attack complex|attack complex]] that lead to the [[lysis]] of the ...

{{Short description|Protein complex involved in the complement system}} | Name = complement component 4 binding protein, alpha ...

...mplement proteins further down the cascade. In contrast to the [[classical complement pathway]], the [[lectin]] pathway does not recognize an antibody bound to i ...ollectin]] family that is produced by the [[liver]] and can initiate the [[complement cascade]] by binding to [[pathogen]] surfaces. ...

...Wang Y, Qin X, Liang S | display-authors = 6 | title = Target deletion of complement component 9 attenuates antibody-mediated hemolysis and lipopolysaccharide ( ....2007.05.005 }}</ref> In fish, the liver is the site where the majority of complement components are produced and expressed, but C9 can also be found in other ti ...

* [[Complement factor D]], an enzyme * [[Congenital Femoral Deficiency]], a birth defect ...

...encoded by the ''C5'' [[gene]].<ref name="entrez">{{cite web | title = C5 complement C5 (Homo sapiens (human)) Gene ID: 727 |date= 29 November 2020| url = https ...component 5 is involved in the [[complement system]]. It is cleaved into [[Complement component 5a|C5a]] and C5b: ...

...]] of the [[complement system]], acting as a multi-domain serine protease. Deficiency of C2 has been associated with certain autoimmune diseases.<ref name="entre ...n [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923430/ immune response.] Complement component 2 protein is critical for regulating the body's immune response. ...

...name="entrez">{{cite web | title = Entrez Gene: complement component 6 C6 complement C6 (Homo sapiens (human)) Gene ID: 729 |date= 24 November 2020| url = https Complement component 6 is a protein involved in the [[complement system]]. It is part of the membrane attack complex which can insert into t ...

| synonyms = MPO deficiency ...ometry]] or cytochemical stains. There is no treatment for myeloperoxidase deficiency itself. Rather, in the rare cases that individuals experience symptoms, the ...

| name = Protein S deficiency | causes = Vitamin K deficiency<ref name=pat/> ...

...= free }}</ref><ref name="entrez_718">{{cite web | title = Entrez Gene: C3 complement component 3 | url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=S ...2">{{cite journal | vauthors = Geisbrecht BV, Lambris JD, Gros P | title = Complement component C3: A structural perspective and potential therapeutic implicatio ...

{{further|Subject complement|I (pronoun)#Functions}} ...ref name="Nesfield1922" /> "It" was used as the [[Complement (linguistics)|complement]] of "am", but in modern English "it" is the [[Subject (grammar)|subject]]. ...

| name = Leukocyte-adhesion deficiency ...r=2011 |title=A novel leukocyte adhesion deficiency III variant: kindlin-3 deficiency results in integrin- and nonintegrin-related defects in different steps of ...

...omplement Complex C5b-9).png|thumb|right|Membrane attack complex (Terminal complement complex C5b-9)]] [[Image:complement death.PNG|thumb|right|A membrane attack complex attached to a pathogenic ce ...

...encoded by the ''C1S'' [[gene]].<ref>{{cite web | title = Entrez Gene: C1S Complement component 1, s subcomponent| url = https://www.ncbi.nlm.nih.gov/sites/entre ...ponent 2|C2]], which eventually leads to the production of the [[classical complement pathway|classical]] pathway [[C3-convertase]]. ...

[[File:Complement pathways.png|thumb|393x393px|Classical and alternative pathways shown with ...d [[Immunoglobulin M|IgM]].<ref name="Overview of Complement" /><ref name="Complement in disease" /> ...

...''C1R'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: C1R complement component 1, r subcomponent| url = https://www.ncbi.nlm.nih.gov/gene?Db=gen ...[C1s]] form the [[C1 complex]], which is the first component of the serum complement system. C1r is an [[enzyme]] that activates C1s to its active form, by [[pr ...

...occur in, for example, [[ataxia–telangiectasia]], [[complement deficiency|complement deficiencies]], many types of [[cancer]], and certain chronic infections su [[B cell]] deficiency and [[T cell]] deficiency are immune impairment that individuals are born with or are acquired, which ...

| Name = complement factor D (adipsin) ...X, Bugg CE, Volanakis JE, DeLucas LJ |title=Structure of human factor D. A complement system protein at 2.0 A resolution |journal=Journal of Molecular Biology |v ...