Complement component 1s

Template:Cs1 config Template:Short description Template:Infobox gene Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system. C1s is part of the C1 complex. In humans, it is encoded by the C1S gene.

C1s cleaves C4 and C2, which eventually leads to the production of the classical pathway C3-convertase.

File:Droga klasyczna.png

Classical pathway. (Some labels are in Polish.)

See also

• C1q - another part of the C1 complex
• C1r - another part of the C1 complex
• MASP-2 - a protein similar to C1s, part of the lectin pathway

External links

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• Template:UCSC gene info

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