Sivelestat

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Template:Short description Template:Drugbox

Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase.[1]

It is used in the treatment of acute respiratory failure[2] and preliminary studies show it may also improve neuropathic pain.[3]

Synthesis

Sivelestat is synthesised as follows:[4]

File:Sivelestat scheme.png

References

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