Siskiyou

Siskiyou may refer to:

• Siskiyou Mountains, a mountain range in northern California and southern Oregon
• Siskiyou National Forest, in Oregon and California
• Siskiyou County, California
• Siskiyou Trail, an old Native American and pioneer trail connecting Oregon and California
• Siskiyou Summit, a mountain pass () on Interstate 5 in southern Oregon
• Siskiyou Mountains salamander
• Siskiyou (newspaper), a student-run newspaper at Southern Oregon University in Ashland, Oregon.
• Siskiyou (band), a Canadian indie folk band.