Santa Clara

Template:Sister project Santa Clara (Portuguese and Spanish for Saint Clare or Saint Clair) may refer to:

Places

Santa Clara County, California, in the San Francisco Bay Area
- Santa Clara, California, a city within the county
  - Santa Clara Transit Center, in the city
  - Santa Clara University, in the city
    - Mission Santa Clara de Asís, origin of the city and county, now surrounded by the university
- Santa Clara station (VTA), a light rail station on Santa Clara Street in San Jose, the largest city in Santa Clara County
- Santa Clara Valley, better known as "Silicon Valley", including Santa Clara County and other counties
- Santa Clara Valley AVA, a wine region primarily in the county
Santa Clara River (California), in Ventura and Los Angeles counties in Southern California
- Santa Clara River Valley, in Ventura County
Santa Clara station (Metrorail), Allapattah, Miami, Florida
Santa Clara, New Mexico
Santa Clara Indian Reservation, New Mexico
- Santa Clara Pueblo, New Mexico
Santa Clara, New York
Santa Clara, Eugene, Oregon
Santa Clara, Texas
Santa Clara, Utah
Santa Clara River (Utah)
Santa Clara Volcano, Utah

Santa Clara (baseball club), a Cuban team from 1922 to 1941, known as the Leopards
C.D. Santa Clara de El Salvador, a football club in Pasaquina, La Union
C.D. Santa Clara, a football club in Santa Clara, Ponta Delgada, Azores

Niña, or Santa Clara, one of the three ships on Christopher Columbus's first voyage
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The Santa Clara, the student newspaper of Santa Clara University, California
Battle of Santa Clara, a 1958 conflict in Cuba