STEAP3

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Template:Short description Template:Infobox gene Metalloreductase STEAP3 is an enzyme that in humans is encoded by the STEAP3 gene.[1][2]

STEAP3 is a metalloreductase, capable of converting iron from an insoluble ferric (Fe3+) to a soluble ferrous (Fe2+) form.[3]

STEAP3 and other STEAP protein, with the exception of STEAP1, are predicted to contain a Di-nucleotide binding domain (Rossmann Fold). This has been shown using X-ray crystallography in the cases of STEAP3 and STEAP4 (PDB: 2VNS, 2VQ3 and 2YJZ).[4][5]

Interactions

STEAP3 has been shown to interact with BNIP3L[1] and PKMYT1.[1]

References

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Further reading

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