SSH3

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Template:Short description

Template:Infobox gene Protein phosphatase Slingshot homolog 3 is an enzyme that in humans is encoded by the SSH3 gene.[1][2]

Function

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002).[supplied by OMIM][2]

References

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Further reading

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