SPK

SPK may refer to:

• SPK (band), Australia
• SPK, Soviet cosmonaut maneuvering unit
• Simultaneous pancreas-kidney transplant, a type of pancreas transplantation
• Socialist Patients' Collective (Template:Langx)
• Postal code for Spinola Park, St. Julian's, Malta
• Stiftung Preußischer Kulturbesitz, the Prussian Cultural Heritage Foundation
• Strategic Plan Campine (Template:Langx)
• Sutton Parkway railway station's station code