SPIB
Template:Short description Template:Infobox gene Transcription factor Spi-B is a protein that in humans is encoded by the SPIB gene.[1][2]
Function
SPI1 (MIM 165170) and SPIB are members of a subfamily of ETS (see ETS1; MIM 164720) transcription factors. ETS proteins share a conserved ETS domain that mediates specific DNA binding. SPIB and SPI1 bind to a purine-rich sequence, the PU box (5-prime-GAGGAA-3-prime).[supplied by OMIM][2]
Interactions
SPIB has been shown to interact with MAPK3[3] and MAPK8.[3]
References
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Further reading
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External links
- Template:Replace at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.