SNX5
Template:Short description Template:Infobox gene Sorting nexin-5 is a protein that in humans is encoded by the SNX5 gene.[1][2][3]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein is a component of the mammalian retromer complex,[2] which facilitates cargo retrieval from endosomes to the trans-Golgi network. It has also been shown to bind to the Fanconi anemia, complementation group A protein. This gene results in two transcript variants encoding the same protein.[3]
Interactions
SNX5 has been shown to interact with FANCA.[1]
References
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Further reading
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