SLA2

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Template:Short description Template:Infobox gene Src-like-adapter 2 is a protein that in humans is encoded by the SLA2 gene.[1][2]

Function

This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.[2]

Interactions

SLA2 has been shown to interact with Cbl gene.[3]

References

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Further reading

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