SHROOM3
Template:Short description Template:Infobox gene Protein shroom3 also known as shroom-related protein is a protein that in humans is encoded by the SHROOM3 gene.[1][2][3]
Protein shroom3 is a PDZ domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues.
Clinical relevance
Mutations in this gene have been shown to cause heterotaxy.[4] A similar protein in mice is required for proper neurulation,[1][3] eye,[5] and gut development.[6][7]
References
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Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.