SF3B6

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Template:Short description Template:Infobox gene Splicing factor 3B subunit 6, is a protein encoded by SF3B6 gene in vertebrates.[1]

Function

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.[1]

Interactions

SF3B14 has been shown to interact with SF3B1.[2][3]

References

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Further reading

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