Roseophilin
Jump to navigation
Jump to search
Roseophilin is an antibiotic isolated from Streptomyces griseoviridis shown to have antitumor activity.[1] The chemical structure can be considered in terms of two components, a macrotricyclic segment and a heterocyclic side-chain. Several laboratory syntheses of roseophilin (e.g., those of Trost, Fürstner, Salamone) are based upon the Paal-Knorr synthesis, and two others are based on the Nazarov cyclization reaction (those of Tius, Frontier). The compound is related to the prodiginines.[2]
References
<templatestyles src="Reflist/styles.css" />
Script error: No such module "Check for unknown parameters".