RIT1

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Template:Short description Template:Infobox gene GTP-binding protein Rit1 is a protein that in humans is encoded by the RIT1 gene.[1][2][3]

Function

RIT belongs to the RAS (HRAS; MIM 190020) subfamily of small GTPases (Hynds et al., 2003).[supplied by OMIM][3]

Clinical significance

Mutations in RIT1 are associated to Noonan syndrome.[4]

Interactions

RIT1 has been shown to interact with KLHL12[5] and Merlin.[6]

References

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Further reading

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