RFX3

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Template:Short description

Template:Infobox gene Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.[1][2]

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.[2]

References

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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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