RASGRF2

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Template:Short description Template:Cs1 config Template:Infobox gene Ras-specific guanine nucleotide-releasing factor 2 is a protein that in humans is encoded by the RASGRF2 gene.[1]

RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.[supplied by OMIM][1]

Variations in this gene has been shown to be linked to the propensity to binge drink by teenagers.[2]

References

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Further reading

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