RAB5A

Template:Cs1 config Template:Short description Template:Infobox gene Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.

Function

RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to early endosomes. It drives the maturation of endosomes by transporting vacuolar (H+)-ATPases (V-ATPases) from trans-Golgi network to endocytic vesicles.

Interactions

RAB5A has been shown to interact with:

• CHML,
• RABEP1,
• SDCBP, and
• ZFYVE20