Prokineticin

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Prokineticin is a secreted protein that potently contracts gastrointestinal smooth muscle.[1]

Recently, prokineticins have been recognized in humans and other vertebrates.[2] They are thought to be involved in several important physiological processes like neurogenesis, tissue development, angiogenesis, and nociception.[2][3] Other important physiological roles the Bv8/Prokineticins (PKs) are involved in may include cancer, reproduction, and regulating physiological functions that influence circadian rhythms like hormone secretion, ingestive behaviors, and the sleep/wake cycle.[4]

Mutations in the PROK2 (also known as KAL4) gene have been implicated in hypogonadotropic hypogonadism and gynecomastia.[5]

See also

References

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  3. Liu B, Qiao L, Liu K, Piccinni-Ash TJ, Chen ZF. Molecular and neural basis of pleasant touch sensation. Science 2022; 376(6592):483. Script error: No such module "CS1 identifiers".
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External links

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