Prehormone
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A prehormone is a biochemical substance secreted by glandular tissue and has minimal or no significant biological activity, but it is converted in peripheral tissues into an active hormone. Calcifediol is an example of a prehormone which is produced by hydroxylation of vitamin D3 (cholecalciferol) in the liver.[1] Another example is adrenal androgens like dehydroepiandrosterone and androstenedione, which can be converted into testosterone and dihydrotestosterone.[2]
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