Piperocaine

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Piperocaine is a local anesthetic drug developed in the 1920s and used as its hydrochloride salt for infiltration and nerve blocks.

Synthesis

File:Piperocaine synthesis.svg
Synthesis:[1] Patent:[2]

Alkylation between 3-chloropropyl benzoate [942-95-0] (1) and Pipicoline [109-05-7] (2) provides piperocaine (3).

See also

References

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  1. ↑ McElvain, S. M. (1927). "PIPERIDINE DERIVATIVES IV. SUBSTITUTED PIPERIDINE-ALKYL BENZOATES AND PARA-AMINOBENZOATES". Journal of the American Chemical Society 49 (11): 2835–2840. doi:10.1021/ja01410a030.
  2. ↑ Samuel M Mcelvain, U.S. patent 1784903 (1930).

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Further reading

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  1. ↑ Script error: No such module "Citation/CS1".
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